Patients with mild to moderate hepatic dysfunction due to liver metastases should be carefully monitored when xeloda is administered.

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Based on postmarketing reportspatients with certain homozygous or certain compound heterozygous mutations in the DPD gene that result in complete or near complete absence of DPD activity are at increased risk for acute early-onset of toxicity and severelife-threateningor fatal adverse reactions caused by XELODAe.gmucositisdiarrheaneutropeniaand neurotoxicityPatients with partial DPD activity may also have increased risk of severelife-threateningor fatal adverse reactions caused by XELODA.

Based on postmarketing reportspatients with certain homozygous or certain compound heterozygous levothyroxine 75 mcg online order. mutations in the DPD gene that result in complete or near complete absence of DPD activity are at increased risk for acute early-onset of toxicity and severelife-threateningor fatal adverse reactions caused by XELODAe.gmucositisdiarrheaneutropeniaand neurotoxicityPatients with partial DPD activity may also have increased risk of severelife-threateningor fatal adverse reactions caused by XELODA.

The chemotherapy drug capecitabine is included in a group of drugs known as anti-metabolitesThis group is focused on stopping the formation of new cancer cells and disrupting the DNA repair processwhich is how cancer cells are able to grow and multiplyCapecitabine is used for the treatment of a number of cancersincluding the breastbowelstomachpancreasand esophagus.

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no xeloda dose has been proven safe in patients with absent dpd activity.